PD Dr. Jan M. Deussing

Primary research focus: Cellular & Systems Neuroscience

Second research focus: Behavioral & Cognitive Neuroscience

Third research focus: Molecular & Developmental Neuroscience

GSN students

Current: Simon Chang, Lidia Urbina Treviño, Clemens Ries

Graduated: Laura Sotillos Elliott

Selected publications:

Chang S, Federica F, Lao C-L, Huang L, Jakovcevski M, Di Giaimo R, Gagliardi M, Menegaz D, Hennrich AA, Ziller M, Eder M, Klein R, Cai N, Deussing JM. Tripartite extended amygdala - basal ganglia CRH circuit drives locomotor activation and avoidance behavior, Sci Adv. [in press]

von Mücke-Heim IA, Ries, Urbina-Treviño L, Bordes J, Schmidt MV, C Deussing JM (2022) Introducing a depression-like syndrome for translational neuropsychiatry: a plea for taxonomical validity and improved comparability between humans and mice. Mol Psychiatry [Epub ahead of print]

Dedic N, Kühne C, Jakovcevski M, Hartmann J, Genewsky AJ, Gomes K.S., Anderzhanova E., Pöhlmann M.L., Chang S., Kolarz A., Vogl A.M., Metzger MW, Schmid B, Almada RC, Ressler KJ, Wotjak CT, Grinevich V, Chen A, Schmidt MV, Wurst W, Refojo D, Deussing JM (2018) Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety. Nat. Neurosci. 21:803-807.

Deussing JM, Chen A (2018) The corticotropin-releasing factor family: Physiology of the stress response. Physiol Rev 98:2225-2286.

Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom D, Schütz G, Nave K-A, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM (2011) Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1. Science 333, 1903-1907.