Prof. Dr. Ali Ertürk

Keywords: Tissue clearing, Spatial-omics, Imaging, Organoids, Neurodegeneration, Cancer, Nanotechnology, Delivery

Research aim: Developing and combining unbiased & scalable technologies for better diagnostics and therapeutics

Three major research areas in our institute are:

Neuroscience
Studying the role of skull-meninges connections we recently found (Cai...Ertürk, 2019, Nature Neuroscience)
Mapping the human brain using SHANEL transparency that we developed (Zhao...Ertürk, 2019, bioRxiv)

Cancer
Implementing DeepMACT method we developed to develop better cancer treatments (Pan...Ertürk, Cell, 2019)

Tissue Engineering
Generating large-scale human tissue and organs using 3D-bioprinting technologies based on the cellular maps we can generate using our DISCO and SHANEL clearing technologies

Graduated: Dr. Chenchen Pan, Dr. Ruiyao Cai, Dr. Mihail Todorov, Dr. Ilgin Kolabas

Selected publications:

• Bhatia...Ertürk A. Spatial proteomics in optically cleared pre-clinical & clinical specimens, Cell (in press) (cover)

• Cai M…Ertürk A. Cellular level whole mouse imaging with vDISCO…Nat. Protocols (in press)

• Kolobas I…Ertürk A. Multi-omics and 3D-imaging reveal bone heterogeneity…(bioRxiv)

• Mai…Ertürk A. Scalable SHANEL Tissue Labelling and Clearing…Nat. Protocols (Oct 2022)

• Todorov M…Ertürk A. Machine learning analysis of whole mouse brain vasculature. Nature Methods, Apr. 2020

• Zhao S…Ertürk A. Cellular and Molecular Probing of Intact Human Organs. Cell, Feb. 2020 (video)

• Pan C…Ertürk A. Deep learning reveals cancer metastasis & therapeutic antibody… Cell, Dec. 2019 (cover) (video)

• Cai R…Ertürk A. Panoptic imaging of transparent mice reveals… Nature Neuroscience, Feb. 2019 (cover)